New insights regarding the autoxidation of polyunsaturated fatty acids.

  title={New insights regarding the autoxidation of polyunsaturated fatty acids.},
  author={Huiyong Yin and Ned A. Porter},
  journal={Antioxidants & redox signaling},
  volume={7 1-2},
Free radical-initiated autoxidation of polyunsaturated fatty acids (PUFAs) has been implicated in numerous human diseases, including atherosclerosis and cancer. This review covers the free radical mechanisms of lipid oxidation and recent developments of analytical techniques to analyze the lipid oxidation products. Autoxidation of PUFAs generates hydroperoxides as primary oxidation products, and further oxidation leads to cyclic peroxides as secondary oxidation products. Characterization of… CONTINUE READING
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