New insights into visceral hypersensitivity—clinical implications in IBS

  title={New insights into visceral hypersensitivity—clinical implications in IBS},
  author={QiQi Zhou and G. Nicholas Verne},
  journal={Nature Reviews Gastroenterology &Hepatology},
A subset of patients with IBS have visceral hypersensitivity and/or somatic hypersensitivity. Visceral hypersensitivity might have use as a clinical marker of IBS and could account for symptoms of urgency for bowel movements, bloating and abdominal pain. The mechanisms that lead to chronic visceral hypersensitivity in patients who have IBS are unclear. However, several working models may be considered, including: nociceptive input from the colon that leads to hypersensitivity; increased… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
34 Citations
67 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 34 extracted citations


Publications referenced by this paper.
Showing 1-10 of 67 references

inhibition processes in irritable bowel syndrome

  • B. Naliboff
  • 2010

rationale, strategies, and challenges

  • R. Garson, G. Marcucci, Croce, C. M. Targeting microRNAs in cancer
  • Nat. Rev. Drug Discov. 9, 775–789
  • 2010

Similar Papers

Loading similar papers…