New insights into the vascular mechanisms underlying the beneficial effect of swimming training on the endothelial vasodilator function in apolipoprotein E-deficient mice.

@article{Pellegrin2007NewII,
  title={New insights into the vascular mechanisms underlying the beneficial effect of swimming training on the endothelial vasodilator function in apolipoprotein E-deficient mice.},
  author={Maxime Pellegrin and Alain Berthelot and Christophe Houdayer and Vincent Gaume and Val{\'e}rie Deckert and Pascal Laurant},
  journal={Atherosclerosis},
  year={2007},
  volume={190 1},
  pages={35-42}
}
The antiatherogenic role of exercise is poorly understood. We examined the swimming exercise-induced vascular mechanisms which enhance the endothelial vasodilator function in apoE(-/-) mice. Male apoE(-/-) mice treated for 9 weeks with a lipid-rich diet were divided into two groups: the exercise group (apoE(-/-) X), which underwent a 9-week swimming protocol (50 min/day; 5days/week) and the sedentary group (apoE(-/-) S). C57BL/6 mice were used as the control group. Atherosclerotic lesions in… CONTINUE READING
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