New insights into the pathophysiology of postoperative cognitive dysfunction.

@article{Krenk2010NewII,
  title={New insights into the pathophysiology of postoperative cognitive dysfunction.},
  author={Lene Krenk and L S Rasmussen and Henrik Kehlet},
  journal={Acta anaesthesiologica Scandinavica},
  year={2010},
  volume={54 8},
  pages={951-6}
}
There is evidence that postoperative cognitive dysfunction (POCD) is a significant problem after major surgery, but the pathophysiology has not been fully elucidated. The interpretation of available studies is difficult due to differences in neuropsychological test batteries as well as the lack of appropriate controls. Furthermore, there are no internationally accepted criteria for defining POCD. This article aims to provide an update of current knowledge of the pathogenesis of POCD with a… CONTINUE READING

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