New insights into the pathogenesis and therapeutics of episodic ataxia type 1

@inproceedings{DAdamo2015NewII,
  title={New insights into the pathogenesis and therapeutics of episodic ataxia type 1},
  author={Maria Cristina D’Adamo and Sonia Hasan and Luca Guglielmi and Ilenio Servettini and Marta Cenciarini and Luigi Catacuzzeno and Fabio Franciolini},
  booktitle={Front. Cell. Neurosci.},
  year={2015}
}
Episodic ataxia type 1 (EA1) is a K(+) channelopathy characterized by a broad spectrum of symptoms. Generally, patients may experience constant myokymia and dramatic episodes of spastic contractions of the skeletal muscles of the head, arms, and legs with loss of both motor coordination and balance. During attacks additional symptoms may be reported such as vertigo, blurred vision, diplopia, nausea, headache, diaphoresis, clumsiness, stiffening of the body, dysarthric speech, and difficulty in… CONTINUE READING