New insights into the mechanisms of antidepressant therapy.

@article{Schloss2004NewII,
  title={New insights into the mechanisms of antidepressant therapy.},
  author={Patrick Schloss and Fritz A. Henn},
  journal={Pharmacology & therapeutics},
  year={2004},
  volume={102 1},
  pages={
          47-60
        }
}
Depressive disorders are among the most frequent psychiatric diseases in the Western world with prevalence numbers between 9% and 18%. They are characterized by depressed mood, a diminished interest in pleasurable activities, feelings of worthlessness or inappropriate guilt, decrease in appetite and libido, insomnia, and recurrent thoughts of death or suicide. Among other findings, reduced activity of monoaminergic neurotransmission has been postulated to play a role in the pathogenesis of… CONTINUE READING

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