New insights into the effects of primary hyperparathyroidism on the cortical and trabecular compartments of bone.

@article{Vu2013NewII,
  title={New insights into the effects of primary hyperparathyroidism on the cortical and trabecular compartments of bone.},
  author={Thuy D T Vu and Xiao Fang Wang and Qingju Wang and Natalie E Cusano and Dinaz K. Irani and Barbara Campolina Silva and Ali Ghasem-Zadeh and Julia Udesky and Megan E. Romano and Roger M D Zebaze and George Jerums and Stephanie Boutroy and John P. Bilezikian and Ego Seeman},
  journal={Bone},
  year={2013},
  volume={55 1},
  pages={
          57-63
        }
}
  • Thuy D T Vu, Xiao Fang Wang, +11 authors Ego Seeman
  • Published in Bone 2013
  • Biology, Medicine
  • In primary hyperparathyroidism (PHPT), protracted elevation of serum parathyroid hormone (PTH) is held to be associated with cortical, but not trabecular, bone loss. However, an alternative explanation for the apparent preservation of trabecular bone is fragmentation of the cortex by intracortical remodeling. The cortical fragments resemble trabeculae and so may be erroneously included in the quantification of 'trabecular' bone density. To test this hypothesis, we compared bone… CONTINUE READING

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