New insights into structure and replication of the hepatitis C virus and clinical implications.

@article{Poenisch2010NewII,
  title={New insights into structure and replication of the hepatitis C virus and clinical implications.},
  author={Marion Poenisch and Ralf Bartenschlager},
  journal={Seminars in liver disease},
  year={2010},
  volume={30 4},
  pages={333-47}
}
With the advent of efficient systems to propagate the hepatitis C virus (HCV) in cultured cells important new discoveries have been made. For instance, several molecules required for HCV infection of hepatocytes have been identified and first insights into the entry pathway have been gained. Ribonucleic acid (RNA) replication and virion assembly were found to be tightly linked to lipid metabolism and numerous host factors contributing to viral replication have been identified. Some of them such… CONTINUE READING

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