New insights into saccular development and vascular formation in lung allografts under the renal capsule

Abstract

The study of distal lung morphogenesis and vascular development would be greatly facilitated by an in vitro or ex vivo experimental model. In this study we show that the growth of mouse embryonic day 12.5 lung rudiments implanted underneath the kidney capsules of syngeneic or immunodeficient hosts follows closely lung development in utero. The epithelium… (More)
DOI: 10.1016/S0925-4773(02)00451-3

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