New insights into process understanding of solid lipid extrusion (SLE) of extruded lipid implants for sustained protein delivery.

@article{Vollrath2018NewII,
  title={New insights into process understanding of solid lipid extrusion (SLE) of extruded lipid implants for sustained protein delivery.},
  author={Moritz Vollrath and Julia Engert and Gerhard Winter},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2018}
}
The aim of this work is a better understanding of solid lipid extrusion (SLE) for protein depot production using a lab-scale twin-screw (tsc) extruder. In this context, little is known about the relationship of process parameters such as extrusion temperature, screw speed, or formulation on implant characteristics. It is difficult to attribute release… CONTINUE READING