New insights into postrenal transplant hemolytic uremic syndrome

@article{Zuber2011NewII,
  title={New insights into postrenal transplant hemolytic uremic syndrome},
  author={J. Zuber and M. L. Quintrec and R. Sberro-Soussan and C. Loirat and V. Fr{\'e}meaux-Bacchi and C. Legendre},
  journal={Nature Reviews Nephrology},
  year={2011},
  volume={7},
  pages={23-35}
}
After renal transplantation, hemolytic uremic syndrome (HUS) may occur either as a recurrent or de novo form. Over the past decade, much effort has been devoted to elucidating the pathogenesis of atypical HUS (aHUS). Approximately 60–70% patients with aHUS have mutations in regulatory factors of the complement system or antibodies against complement factor H. The risk of post-transplant recurrence of aHUS depends on the genetic abnormality involved, and ranges from 15% to 20% in patients with… Expand
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