New insights into mitral heart valve prolapse after chordae rupture through fluid–structure interaction computational modeling

@article{Caballero2018NewII,
  title={New insights into mitral heart valve prolapse after chordae rupture through fluid–structure interaction computational modeling},
  author={A. Caballero and W. Mao and R. McKay and C. Primiano and S. Hashim and Wei Sun},
  journal={Scientific Reports},
  year={2018},
  volume={8}
}
  • A. Caballero, W. Mao, +3 authors Wei Sun
  • Published 2018
  • Medicine
  • Scientific Reports
  • Mitral valve (MV) dynamics depends on a force balance across the mitral leaflets, the chordae tendineae, the mitral annulus, the papillary muscles and the adjacent ventricular wall. Chordae rupture disrupts the link between the MV and the left ventricle (LV), causing mitral regurgitation (MR), the most common valvular disease. In this study, a fluid-structure interaction (FSI) modeling framework is implemented to investigate the impact of chordae rupture on the left heart (LH) dynamics and… CONTINUE READING
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