New insights into cyclins, CDKs, and cell cycle control.

  title={New insights into cyclins, CDKs, and cell cycle control.},
  author={Irma S{\'a}nchez and Brian D. Dynlacht},
  journal={Seminars in cell & developmental biology},
  volume={16 3},
Since their initial discovery in yeast, cyclin-dependent kinases have proven to be universal regulators of the cell cycle in all eukaryotes. In unicellular eukaryotes, cell cycle progression is principally governed by one catalytic subunit (cyclin-dependent kinase) that pairs with cell cycle-specific regulatory subunits known as cyclins. Progression through a specific phase of the cell cycle is under the control of a specific class of cyclin. Cell cycle control in multicellular eukaryotes has… CONTINUE READING

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