New insights into Shiga toxin-mediated endothelial dysfunction in hemolytic uremic syndrome

@inproceedings{PetruzzielloPellegrini2013NewII,
  title={New insights into Shiga toxin-mediated endothelial dysfunction in hemolytic uremic syndrome},
  author={Tania N. Petruzziello-Pellegrini and Mozhgan Moslemi-Naeini and Philip Anthony Marsden},
  booktitle={Virulence},
  year={2013}
}
Shiga toxin-producing E. coli represents a significant global health concern, especially as hypervirulent pathogens surface amidst outbreaks of hemolytic uremic syndrome (HUS). Shiga toxin (Stx) is key in the microangiopathic events underlying the disease and its central role is underscored by the unprecedented HUS outbreak in Germany in 2011. The mechanisms of Stx-mediated endothelial dysfunction have been a major focus of research that has contributed to the current understanding of the… CONTINUE READING

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