New insights and perspectives on intrarenal renin-angiotensin system: Focus on intracrine/intracellular angiotensin II

@article{Zhuo2011NewIA,
  title={New insights and perspectives on intrarenal renin-angiotensin system: Focus on intracrine/intracellular angiotensin II},
  author={Jia Long Zhuo and Xiao Chun Li},
  journal={Peptides},
  year={2011},
  volume={32},
  pages={1551-1565}
}
  • Jia Long Zhuo, Xiao Chun Li
  • Published in Peptides 2011
  • Medicine, Biology
  • Although renin, the rate-limiting enzyme of the renin-angiotensin system (RAS), was first discovered by Robert Tigerstedt and Bergman more than a century ago, the research on the RAS still remains stronger than ever. The RAS, once considered to be an endocrine system, is now widely recognized as dual (circulating and local/tissue) or multiple hormonal systems (endocrine, paracrine and intracrine). In addition to the classical renin/angiotensin I-converting enzyme (ACE)/angiotensin II (Ang II… CONTINUE READING

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