New in vitro model of traumatic neuronal injury: evaluation of secondary injury and glutamate receptor-mediated neurotoxicity.

@article{Mukhin1997NewIV,
  title={New in vitro model of traumatic neuronal injury: evaluation of secondary injury and glutamate receptor-mediated neurotoxicity.},
  author={Alexey G. Mukhin and Svetlana A. Ivanova and Susan Knoblach and Alan I. Faden},
  journal={Journal of neurotrauma},
  year={1997},
  volume={14 9},
  pages={
          651-63
        }
}
The multiplicity and complexity of secondary injury processes following brain trauma in vivo make it difficult to elucidate the roles of specific injury mechanisms. As with other areas of CNS injury, such as ischemia, this has led to the development of in vitro models. Here we describe a new trauma model, in which standardized trauma is delivered to neuronal/glial cultures using a special mechanical device that produces concentric circular cuts in the cell layer. Changes in the number of… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 31 CITATIONS

Stretch-Induced Deformation as a Model to Study Dopaminergic Dysfunction in Traumatic Brain Injury

Hector Rosas-Hernandez, Susan M. Burks, E Gustavo Cuevas, S. Fatehyab Ali
  • Neurochemical Research
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

The Anti-Inflammatory Effects of Interferon Tau by Suppressing NF-κB/MMP9 in Macrophages Stimulated with Staphylococcus aureus.

  • Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
  • 2016