New hypothesis on the role of alternating sequences in calcium-alginate gels.

@article{Donati2005NewHO,
  title={New hypothesis on the role of alternating sequences in calcium-alginate gels.},
  author={Ivan Donati and Synn\ove Holtan and Yrr A M\orch and Massimiliano Antonio Borgogna and Mariella Dentini and Gudmund Skj{\aa}k-Braek},
  journal={Biomacromolecules},
  year={2005},
  volume={6 2},
  pages={1031-40}
}
The availability of mannuronan and mannuronan C-5 epimerases allows the production of a strictly alternating mannuronate-guluronate (MG) polymer and the MG-enrichment of natural alginates, providing a powerful tool for the analysis of the role of such sequences in the calcium-alginate gel network. In view of the calcium binding properties of long alternating sequences revealed by circular dichroism studies which leads eventually to the formation of stable hydrogels, their direct involvement in… CONTINUE READING