New hydrazones with pyrazolone structure: synthesis, characterization and biological evaluation.

Abstract

AIM To design new hydrazones with pyrazolone structure with improved biological properties. MATERIAL AND METHODS New hydrazones of antipyrine have been prepared by reaction of 4-aminophenazone (4-aminoantipyrine) with chloracetylchoride and hydrazine hydrate and then condensation with various aromatic aldehydes. RESULTS The synthesized compounds were… (More)

Topics

6 Figures and Tables

Cite this paper

@article{Apotrosoaei2013NewHW, title={New hydrazones with pyrazolone structure: synthesis, characterization and biological evaluation.}, author={Maria Apotrosoaei and Ioana Mirela Vasincu and Cristina Gabriela Tuchiluş and Florentina Geanina Lupaşcu and Sandra Constantin and Dan Lupascu and Lenuţa Profire}, journal={Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi}, year={2013}, volume={117 2}, pages={538-44} }