New human and mouse microRNA genes found by homology search

  title={New human and mouse microRNA genes found by homology search},
  author={M. J. Weber},
  journal={The FEBS Journal},
  • M. J. Weber
  • Published 2005
  • Medicine, Biology
  • The FEBS Journal
  • Conservation of microRNAs (miRNAs) among species suggests that they bear conserved biological functions. However, sequencing of new miRNAs has not always been accompanied by a search for orthologues in other species. I report herein the results of a systematic search for interspecies orthologues of miRNA precursors, leading to the identification of 35 human and 45 mouse new putative miRNA genes. MicroRNA tracks were written to visualize miRNAs in human and mouse genomes on the UCSC Genome… CONTINUE READING

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