New helping friends for B cells.

  title={New helping friends for B cells.},
  author={Andrea Cerutti and Irene Puga and Montserrat Cols},
  journal={European journal of immunology},
  volume={42 8},
Over the past decade, a growing recognition of the importance of neutralizing antibodies in host defense combined with the success of B-cell depletion therapies in treating auto-immune disorders has led to an increased focus on better understanding the pathways underpinning B-cell antibody production. In general, B cells require cognate interaction with T helper cells in the germinal center of lymphoid follicles to generate protective antibodies. However, recent evidence shows that B cells… CONTINUE READING


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