New glycosylated conjugate copolymer N-acetyl-β-D-glucosaminyl-pluronic: Synthesis, self-assembly and biological assays.

@article{Frizon2015NewGC,
  title={New glycosylated conjugate copolymer N-acetyl-β-D-glucosaminyl-pluronic: Synthesis, self-assembly and biological assays.},
  author={Tiago Elias Allievi Frizon and Yasmine Miguel Serafini Micheletto and Jos{\'e} Luiz Westrup and Priscila Sayoko Silva Wakabayashi and Francieli Rocha Serafim and Adriani Paganini Damiani and Luiza Martins Longaretti and Vanessa Moraes de Andrade and Fernando C Giacomelli and S{\'e}bastien Fort and Alexandre Gonçalves Dal B{\'o}},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2015},
  volume={133},
  pages={323-30}
}
This work describes the synthesis of a new glycosylated conjugate copolymer, GlcNAc-PEO75-PPO30-PEO75-GlcNAc (GlcNAc-PluronicF68-GlcNAc), using click chemistry from Pluronic(®) F68 and propargyl-2-N-acetamido-2-deoxy-β-D-glucopyranoside. Micelles were prepared by the self-assembly of GlcNAc-PluronicF68-GlcNAc in phosphate-buffered solution. The critical… CONTINUE READING