New global analysis of the microRNA transcriptome of primary tumors and lymph node metastases of papillary thyroid cancer

@inproceedings{Saiselet2015NewGA,
  title={New global analysis of the microRNA transcriptome of primary tumors and lymph node metastases of papillary thyroid cancer},
  author={Manuel Saiselet and David Gacquer and Alex Spinette and Ligia I Craciun and Myriam Decaussin-Petrucci and Guy Andry and Vincent Detours and C. Maenhaut},
  booktitle={BMC Genomics},
  year={2015}
}
Papillary Thyroid Cancer (PTC) is the most prevalent type of endocrine cancer. Its incidence has rapidly increased in recent decades but little is known regarding its complete microRNA transcriptome (miRNome). In addition, there is a need for molecular biomarkers allowing improved PTC diagnosis. We performed small RNA deep-sequencing of 3 PTC, their matching normal tissues and lymph node metastases (LNM). We designed a new bioinformatics framework to handle each aspect of the miRNome: whole… CONTINUE READING
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