New gestational phase-specific cutoff values for the use of the soluble fms-like tyrosine kinase-1/placental growth factor ratio as a diagnostic test for preeclampsia.

@article{Verlohren2014NewGP,
  title={New gestational phase-specific cutoff values for the use of the soluble fms-like tyrosine kinase-1/placental growth factor ratio as a diagnostic test for preeclampsia.},
  author={S Verlohren and I Herraiz and Olav Lapaire and Dietmar Schlembach and Harald Zeisler and Pavel Calda and Joan Sabria and Filiz Markfeld-Erol and Alberto Galindo and Katharina Schoofs and Barbara Denk and Holger Stepan},
  journal={Hypertension},
  year={2014},
  volume={63 2},
  pages={346-52}
}
To establish gestational phase adapted cutoffs for the use of the soluble fms-like tyrosine kinase-1 (sFlt-1)/placental growth factor (PlGF) ratio as a diagnostic tool for preeclampsia in the clinical setting, a multicenter case-control study including a total of 1149 patients was performed. We report normal values of sFlt-1, PlGF, and the sFlt-1/PlGF ratio based on the analysis of a total of 877 patients with uneventful pregnancy outcome. A total of 234 patients with preeclampsia and a matched… CONTINUE READING
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