New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide.

@article{Justino2005NewGI,
  title={New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide.},
  author={Marta C. Justino and Jo{\~a}o B Vicente and Miguel Teixeira and L{\'i}gia M. Saraiva},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 4},
  pages={2636-43}
}
Nitric oxide produced by activated macrophages plays a key role as one of the immune system's weapons against pathogens. Because the lifetime of nitric oxide is short in aerobic conditions, whereas in anaerobic conditions the cytotoxic effects of nitric oxide are greatly increased as in the infection/inflammation processes, it is important to establish which systems are able to detoxify nitric oxide under anaerobic conditions. In the present work a new set of Escherichia coli K-12 genes… CONTINUE READING
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