New genes expressed in human brains: Implications for annotating evolving genomes

@article{Zhang2012NewGE,
  title={New genes expressed in human brains: Implications for annotating evolving genomes},
  author={Yong E Zhang and Patrick Landback and Maria D. Vibranovski and Manyuan Long},
  journal={BioEssays},
  year={2012},
  volume={34}
}
New genes have frequently formed and spread to fixation in a wide variety of organisms, constituting abundant sets of lineage‐specific genes. It was recently reported that an excess of primate‐specific and human‐specific genes were upregulated in the brains of fetuses and infants, and especially in the prefrontal cortex, which is involved in cognition. These findings reveal the prevalent addition of new genetic components to the transcriptome of the human brain. More generally, these findings… 
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