New function of TSGA10 gene in angiogenesis and tumor metastasis: a response to a challengeable paradox.

@article{Mansouri2016NewFO,
  title={New function of TSGA10 gene in angiogenesis and tumor metastasis: a response to a challengeable paradox.},
  author={Kamran Mansouri and Ali Mostafie and Davood Rezazadeh and Mohsen Shahlaei and Mohammad H Modarressi},
  journal={Human molecular genetics},
  year={2016},
  volume={25 2},
  pages={233-44}
}
Several studies have shown that testis-specific gene antigen (TSGA10) could be considered as a cancer testis antigen (CTA), except for one study which has identified it as a tumor suppressor gene. In order to exert its function, TSGA10 interacts closely with hypoxia inducible factor (HIF-1α) and since this interaction is still not completely defined, the… CONTINUE READING