New evidence that an epigenetic mechanism mediates testosterone-dependent brain masculinization.

@article{Baum2009NewET,
  title={New evidence that an epigenetic mechanism mediates testosterone-dependent brain masculinization.},
  author={Michael J Baum},
  journal={Endocrinology},
  year={2009},
  volume={150 9},
  pages={
          3980-2
        }
}
Since the seminal publication of Raisman and Field (1) showing that neonatal exposure to testosterone organizes male-typical features of synaptic relationships in the rat hypothalamus, dozens of studies have reaffirmed the critical role of perinatal testosterone in the masculinization of aspects of brain morphology and function in rats and mice as well as in several other mammalian animal models (2). Several lines of investigation exploring the mechanisms of testosterone action in male-typical… CONTINUE READING

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