New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders

@inproceedings{Vasudevaraju2012NewEO,
  title={New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders},
  author={Padmaraju Vasudevaraju and Erika N. Guerrero and Muralidhar L Hegde and T. B. Collen and Gabrielle B. Britton and K. S. Jagannatha Rao},
  booktitle={Journal of pharmacy & bioallied sciences},
  year={2012}
}
BACKGROUND Deoxyribonucleic acid (DNA) topology plays a critical role in maintaining the integrity of the genome and cellular functions. Although changes in DNA conformation and structural dynamics in the brain have been associated with various neurological disorders, its precise role in the pathogenesis is still unclear. Previous studies from our laboratory have shown that there is a conformational change in the genomic DNA of Parkinson's disease (PD) (B to altered B-DNA) and Alzheimer's… CONTINUE READING
10 Citations
37 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Similar Papers

Loading similar papers…