New evidence for brain angiotensin and for its role in hypertension.

@article{Phillips1983NewEF,
  title={New evidence for brain angiotensin and for its role in hypertension.},
  author={Michael Ian Phillips},
  journal={Federation proceedings},
  year={1983},
  volume={42 10},
  pages={2667-72}
}
Twenty years ago it was demonstrated that angiotensin II (Ang II) acts on the brain, which results in an elevation of blood pressure. Ten years later, reninlike activity was discovered in the brain of the rat and dog, which gave rise to the concept of an endogenous brain renin-angiotensin system. In the periphery, the kidney, liver, and lungs work in unison to produce Ang II. Evidence for brain renin, substrate, converting enzyme, and angiotensins is reviewed. New data indicate that the enzyme… CONTINUE READING