New erythrolides from the Caribbean gorgonian octocoral Erythropodium caribaeorum.

  title={New erythrolides from the Caribbean gorgonian octocoral Erythropodium caribaeorum.},
  author={Darryl Ricardo Banjoo and Baldwin S. Mootoo and Russel S. Ramsewak and Rawatee Sharma and Alan J. Lough and S. Mclean and William F Reynolds},
  journal={Journal of natural products},
  volume={65 3},
Seven new briarane diterpenes, erythrolides K-Q (1-7), as well as the known compounds erythrolides A, B, C, F, and J have been isolated from samples of the Caribbean gorgonian Erythropodium caribaeorumcollected at Buccoo Reef and Flying Reef, Tobago. The structures of the new compounds were determined by high-resolution 1H and 13C NMR spectroscopy utilizing COSY, HMBC, HMQC, and NOESY experiments. The structures of erythrolides K and P were confirmed and their relative stereochemistry… 
11 Citations
Diterpenoids from cultured Erythropodium caribaeorum.
The known antimitotic agent eleutherobin and the briarane diterpenoids erythrolides A and B have been isolated from cultured specimens of Erythropodium caribaeorum in amounts comparable to those
Diterpenes from gorgonian corals.
This review describes 602 new compounds isolated from gorgonian corals, with a focus on the structures of new compounds as well as their biological activity.
Metabolic Profiling of the Soft Coral Erythropodium caribaeorum (Alcyonacea: Anthothelidae) from the Colombian Caribbean Reveals Different Chemotypes
Evaluation of cytotoxic activity against the human cancer cell lines PC-3, MCF7, and A549 showed erythrolides A and B as the more active compounds with IC50 values in the range from 2.45 to 30 μM.
Biomedical potential of unchlorinated Briarane Diterpenes from gorgonians and sea pens
Coral reefs are generally comprised of a complex array of communities that may include many different types of coelenterates such as cnidarians such as hard or stony corals as well as ascidians (tunicates) and sponges.
Cnidaria and Ctenophora–1
The article contains sections titled Simplified Classification of Cnidaria, Hermatypic and AhermatypIC Corals: Coral Bleaching, and Comments on the Origin of Terpenes.
Cnidaria and Ctenophora–2
The article contains sections titled: Membrane Constituents and Secondary Metabolites of Hexacorallia (Anthozoa) Fatty Acids, Oxylipins, and Acetylenic Derivatives Sterols and Ecdysteroids
Marine natural products.
  • D. Faulkner
  • Biology, Medicine
    Natural product reports
  • 2001
This review covers the literature published in 2014 for marine natural products, with 1116 citations referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms.
Natural products with anti-Bredt and bridgehead double bonds.
For the first time, this topic is reviewed in a natural product context and finds that Mother nature has seen fit to construct molecules containing bridgehead double bonds that encompass Bredt's rule.
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The carbocyclic ring system of the aquariolide diterpenes has been synthesized by two routes involving a diastereoselective Pauson-Khand reaction and subsequent ring expansion.
Marine Environmental Metabolomics
This study highlights the complexity of chemical interactions in the marine environment as marine organisms have developed a high diversity of chemical defences to avoid predators and parasites.