New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG)

@article{Ocio2014NewDA,
  title={New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG)},
  author={Enrique Mar{\'i}a Ocio and Paul G Richardson and Sundararasan Vincent Rajkumar and Antonio Palumbo and M V Mateos and Robert Z. Orlowski and Shaji K Kumar and S Usmani and David Malin Roodman and Rub{\'e}n Niesvizky and Hermann Einsele and Kenneth C. Anderson and M A Dimopoulos and Herv{\'e} Avet-Loiseau and U-H Mellqvist and Ingemar Turesson and Giovanni Merlini and Rik Schots and P Mccarthy and Leif P. Bergsagel and Chor Sang Chim and Juan Jos{\'e} Lahuerta and J Jitendrakumar Shah and Anne Reiman and Joe Mikhael and Sonja Zweegman and Sagar Lonial and Ray Comenzo and W J Chng and Phillipe Moreau and Peter Sonneveld and Heinz Ludwig and Brian G. M. Durie and J F San Miguel},
  journal={Leukemia},
  year={2014},
  volume={28},
  pages={525-542}
}
Treatment in medical oncology is gradually shifting from the use of nonspecific chemotherapeutic agents toward an era of novel targeted therapy in which drugs and their combinations target specific aspects of the biology of tumor cells. Multiple myeloma (MM) has become one of the best examples in this regard, reflected in the identification of new pathogenic mechanisms, together with the development of novel drugs that are being explored from the preclinical setting to the early phases of… CONTINUE READING
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