New diterpenoids from Caesalpinia species and their cytotoxic activity.

  title={New diterpenoids from Caesalpinia species and their cytotoxic activity.},
  author={Biswanath Das and Yallamalla Srinivas and Chithaluri Sudhakar and Ibram Mahender and Keetha Laxminarayana and Parigi Raghavendar Reddy and Tuniki Venugopal Raju and Naga Mahesh Jakka and Janapala Venkateswara Rao},
  journal={Bioorganic & medicinal chemistry letters},
  volume={20 9},
Chemical investigation on Caesalpinia crista afforded two new diterpenoids, 6beta-cinnamoyloxy-7beta-acetoxyvouacapen-5alpha-ol and 6beta,7beta-dibenzoyloxyvouacapen-5alpha-ol and on Caesalpiniapulcherrima another new diterpenoid, 12-demethyl neocaesalpin F along with several known constituents. The structures of the new compounds were settled from their 1D and 2D NMR spectral data. The cytotoxicity of these compounds was measured on two different cancer cell lines.