New diterpene alkaloids from the roots of Spiraea japonica.

@article{He2001NewDA,
  title={New diterpene alkaloids from the roots of Spiraea japonica.},
  author={H P He and Y M Shen and Ji Xia Zhang and Guo Ying Zuo and X J Hao},
  journal={Journal of natural products},
  year={2001},
  volume={64 3},
  pages={
          379-80
        }
}
Chemical investigation on an ethanol extract from the roots of Spiraea japonica var. acuta resulted in the isolation of three new diterpene alkaloids named spiramide (1) and spiratine A (2) and spiratine B (3). Structures of 1-3 were elucidated primarily on the basis of 1D and 2D NMR experiments. 
Two New Diterpenoid Lactams from Spiraea japonica var. ovalifolia
Two new diterpenoid alkaloids, spiramilactams A (1) and B (2), were isolated from the basic fraction of a MeOH extract of whole plants of Spiraea japonica var. ovalifolia. Their structures wereExpand
Diterpene alkaloids and diterpenes from Spiraea japonica and their anti-tobacco mosaic virus activity.
Five new naturally occurring natural products, including two atisine-type diterpene alkaloids (1 and 2), two atisane-type diterpenes (3 and 4), and a new natural product spiramine C2 (5), along withExpand
Alkaloids from two species of the genus Aconitum
We investigated the aerial part of Aconitum leucostomum Worosch collected in the Altai Mountains of Xinjiang– Uyghur Autonomous Region of the PRC. Extraction by CHCl3 of the aerial part of the plantExpand
Gelegamines A-E: five new oxindole alkaloids from Gelsemium elegans.
Five new oxindole alkaloids, gelegamines A-E (1-5), were isolated from the roots of Gelsemium elegans. Their structures were extensively elucidated on the basis of spectroscopic analysis. Among them,Expand
Muscarine, imidazole, oxazole, thiazole, Amaryllidaceae and Sceletium alkaloids.
A review with 136 references covers the literature from July 2000 to June 2001 on the isolation, bioactivities, and synthetic highlights of complex natural products including muscarine, imidazole,Expand
Alkaloids from the aerial parts of Consolida anthoroidea and Delphinium linearilobum
1) Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy, 34116 Beyazyt-Istanbul-Turkey, e-mail: alimer@istanbul.edu.tr; fmericli@istanbul.edu.tr; 2) Marmara University, Faculty ofExpand
Intramolecular Modulation of Serine Protease Inhibitor Activity in a Marine Cyanobacterium with Antifeedant Properties
TLDR
This finding suggests that cyanobacteria can endogenously modulate the activity of their protease inhibitors, and is formally derived from an intramolecular condensation of largamide D. Expand
Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica.
TLDR
The results suggest that the atisine-type alkaloids isolated from S. japonica are a class of novel antiplatelet aggregation agents, and the inhibitory effect of spiramine C1 on arachidonic acid was as potent as that of aspirin. Expand
An Explorer of Chemical Biology of Plant Natural Products in Southwest China, Xiaojiang Hao
TLDR
One candidate drug, phenchlobenpyrrone, has entered the Phase II clinical trail for the treatment of Alzheimer’s disease and Professor Hao has obtained one PCT patent and 23 patents in China. Expand
Hemiterpene glucosides and other constituents from Spiraea canescens.
TLDR
Five glycosides isolated from the whole plant of Spiraea canescens showed potent radical scavenging activity in relevant non-physiological assays and their structures were determined by NMR spectroscopic and CID mass spectrometric techniques. Expand
...
1
2
...