New directions in the management of advanced pancreatic cancer: a review

  title={New directions in the management of advanced pancreatic cancer: a review},
  author={C. Rocha-Lima},
  journal={Anti-Cancer Drugs},
  • C. Rocha-Lima
  • Published 2008
  • Medicine
  • Anti-Cancer Drugs
  • Complete surgical resection is the only potentially curative option for pancreatic cancer. However, most patients have advanced/metastatic disease at the time of diagnosis, or will relapse after surgery. Systemic chemotherapy is only palliative. Gemcitabine-based therapy is an acceptable standard for unresectable locally advanced/metastatic pancreatic cancer, but average median survival is only 6 months. The addition of other chemotherapies (including other antimetabolites, platinum, and… CONTINUE READING
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