New directions in ER stress-induced cell death

@article{Logue2013NewDI,
  title={New directions in ER stress-induced cell death},
  author={Susan E Logue and P. W. Cleary and Svetlana Saveljeva and Afshin Samali},
  journal={Apoptosis},
  year={2013},
  volume={18},
  pages={537-546}
}
Endoplasmic reticulum (ER) stress has been implicated in the pathophysiology of many diseases including heart disease, cancer and neurodegenerative diseases such as Alzheimer’s and Huntington’s. Prolonged or excessive ER stress results in the initiation of signaling pathways resulting in cell death. Over the past decade much research investigating the onset and progression of ER stress-induced cell death has been carried out. Owing to this we now have a better understanding of the signaling… CONTINUE READING
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