New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

@article{Poser1983NewDC,
  title={New diagnostic criteria for multiple sclerosis: Guidelines for research protocols},
  author={Charles M. Poser and Donald W. Paty and Labe C. Scheinberg and W. Ian Mcdonald and F. A. Davis and George Cornell Ebers and Kenneth P. Johnson and William A. Sibley and Donald Silberberg and Wallace W. Tourtellotte},
  journal={Annals of Neurology},
  year={1983},
  volume={13}
}
Several schemes for the diagnosis and clinical classification of multiple sclerosis (MS) have been advanced [l}. The best known is that published by Schumacher et alC31. The criteria for this scheme were established in order to select patients for participation in therapeutic trials, and pertain only to what might be called definite MS. No provision was made for incorporating supportive laboratory data into the diagnostic criteria. As no reliable specific laboratory test for the diagnosis of MS… Expand
Diagnostic criteria for multiple sclerosis
TLDR
The history of clinical diagnostic criteria demonstrates the evolution from rather tentative classifications of restricted value to the more elaborate 1983 scheme which incorporates some laboratory procedures under the rubric paraclinical tests as well as a new category based on the presence of specific abnormalities of the cerebrospinal fluid (CSF). Expand
Diagnostic criteria in multiple sclerosis: Headed in the right direction but still a ways to go
TLDR
The 2010 version of the McDonald criteria formally recognize neuromyelitis optica (NMO) as a separate condition, but hedge a bit by stating that the relation between NMO and MS in Asia and Latin America remains unclear. Expand
Assessment and Diagnosis of Relapsing Multiple Sclerosis
TLDR
Although MRI has largely replaced the use of CSF and evoked potential testing in the explicit diagnostic criteria, paraclinical testing may be useful for ruling out alternative disease etiology, and, indeed, diagnostic criteria require that no better explanation for the neurologic symptoms be available. Expand
Diagnostic criteria for multiple sclerosis: an historical review
TLDR
The choice will have to be made by the neurological community between basing the diagnosis of MS on the MRI alone, or to use it as one aspect of a comprehensive clinical diagnostic algorithm. Expand
CLINICAL MANIFESTATIONS OF MULTIPLE SCLEROSIS: Taxonomy and Diagnostic Parameters in Multiple Sclerosis
TLDR
Technical advances in diagnostic capabilities have given many physicians, including neurologists, a false sense of security in diagnosing multiple sclerosis (MS), which has made doctors pay less attention to the history and the neurological examination. Expand
[Diagnosis of multiple sclerosis].
TLDR
The most innovative use of MRI to support an MS diagnosis is dissemination of demyelination can be demonstrated by MRI alone, in the absence of any new clinical attacks, which has added some sensitivity, some controversy, and a lot of confusion. Expand
Diagnosing multiple sclerosis: Recognizing symptoms and diagnostic testing
TLDR
The criteria currently in use are the revised McDonald criteria, which are predominantly based on MRI scanning, and the relevant paraclinical tests are explained in a little more detail. Expand
MRI criteria for MS in patients with clinically isolated syndromes
TLDR
Information that may simplify the existing MS diagnostic criteria, while maintaining a high specificity that is essential to minimize false positive diagnoses is reviewed and discussed and integrated in this position paper. Expand
New diagnostic criteria for multiple sclerosis
TLDR
One year after symptom onset, more than three times as many patients with CIS were diagnosed with MS using new diagnostic criteria incorporating MRI results compared to older criteria, however, the proposed MRI criteria require further prospective studies to optimize sensitivity and specificity. Expand
Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis
TLDR
The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including “monosymptomatic” disease suggestive of MS, disease with a typical relapsing‐remitting course, and disease with insidious progression, without clear attacks and remissions. Expand
...
1
2
3
4
5
...

References

SHOWING 1-3 OF 3 REFERENCES
PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS
TLDR
Since its etiology and pathogenesis have eluded detection, it is not surprising that therapeutic attempts have been empiric and often unscientific. Expand
The design of clinical studies to assess therapeutic efficacy in multiple sclerosis
TLDR
The diagnosis, clinical course, and definitions of the stages of MS are discussed as they relate to trials of therapy, and specific strategies and design considerations be applied to preliminary, pilot, and full trials. Expand
Willmon TL: Problems of experimental trials of therapy in multiple sclerosis
  • Ann NY Acad Sci 122:552-568,
  • 1965