New diagnosis of polycystic ovary syndrome

  title={New diagnosis of polycystic ovary syndrome},
  author={Isabel McLuskie and Aisha Newth},
  journal={British Medical Journal},
#### What you need to know A 27 year old woman with a recent diagnosis of polycystic ovary syndrome comes to see you. She wants to know more about the condition and the consequences for her health (box 1). #### Box 1: Background facts Polycystic ovary syndrome affects 6%-7% of women.1 Women may experience The relation between polycystic ovary syndrome and obesity is poorly understood. Polycystic ovary syndrome is not caused by, and does not cause, obesity. However, obesity is associated… Expand
6 Citations
Natural Molecules in the Management of Polycystic Ovary Syndrome (PCOS): An Analytical Review
This review provides a comprehensive overview of the current knowledge about the efficacy of natural molecule supplementation in the management of PCOS. Expand
The role of serum β-trophin and endostatin in patients with polycystic ovary syndrome: Are they correlated?
Increased β-trophin is closely associated with increased ES in patients with PCOS, which may be the useful indicators for the management of PCOS. Expand
Serum Leptin Concentration is Correlated to Insulin Resistance in Polycystic Ovary Syndrome (PCOS) Patients
There was a significant correlation between serum leptin levels and HOMA-IR values in PCOS patients, and this correlation was found to be significant regardless of patient's BMI, therefore is considered to have a direct effect on insulin resistance in PCos. Expand
Association of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms with genetic susceptibility to polycystic ovary syndrome: A PRISMA-compliant meta-analysis.
The result based on previously published studies demonstrated that T allele in MTHFR C677T polymorphism might be a genetic risk factor for PCOS, especially in the Asian population, which might be contribute to PCOS susceptibility. Expand
Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis
A systematic review and meta-analysis of longitudinal studies linking polycystic ovary syndrome and cardiometabolic disease quantifies this risk, which is important for clinicians to inform patients and to take into account in the cardiovascular risk assessment of women with PCOS. Expand
Downregulation of serum long noncoding RNA GAS5 may contribute to insulin resistance in PCOS patients
Investigation of the relationship between IR and differential expression of lncRNA Growth-arrest specific transcript 5 in patients’ serum with and without PCOS shows that there is a negative association between GAS5 expression and homeostasis model of assessment for insulin resistance (HOMA-IR). Expand


Polycystic ovary syndrome and the risk of gynaecological cancer: a systematic review.
A meta-analysis of the data suggests that women with PCOS appear to be three times more likely to develop endometrial cancer but are not at increased risk of breast cancer, and there is insufficient evidence to implicate PCOS in the development of vaginal, vulval, cervical or ovarian cancers. Expand
Impact of Obesity on female reproductive health: British Fertility Society, Policy and Practice Guidelines
Women should be provided with assistance to lose weight, including psychological support, dietary advice, exercise classes and where appropriate, weight reducing agents or bariatric surgery, to restore fertility and improve metabolic markers. Expand