New developments on the functions of coenzyme Q in mitochondria.

  title={New developments on the functions of coenzyme Q in mitochondria.},
  author={Maria Luisa Genova and Giorgio Lenaz},
  volume={37 5},
The notion of a mobile pool of coenzyme Q (CoQ) in the lipid bilayer has changed with the discovery of respiratory supramolecular units, in particular the supercomplex comprising complexes I and III; in this model, the electron transfer is thought to be mediated by tunneling or microdiffusion, with a clear kinetic advantage on the transfer based on random collisions. The CoQ pool, however, has a fundamental function in establishing a dissociation equilibrium with bound quinone, besides being… CONTINUE READING
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