New developments in the second heart field.

  title={New developments in the second heart field.},
  author={St{\'e}phane Zaffran and Robert G. Kelly},
  journal={Differentiation; research in biological diversity},
  volume={84 1},
During cardiac looping the heart tube elongates by addition of progenitor cells from adjacent pharyngeal mesoderm to the arterial and venous poles. This cell population, termed the second heart field, was first identified ten years ago and many studies in the intervening decade have refined our understanding of how heart tube elongation takes place and identified signaling pathways that regulate proliferation and differentiation during progressive contribution of second heart field cells to the… CONTINUE READING
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