New developments in intracrinology of human breast cancer: estrogen sulfatase and sulfotransferase.

Abstract

Steroid sulfatase (STS) hydrolyses biologically inactive estrogen sulfates to active estrogens, while estrogen sulfotransferase (EST) sulfonates estrogens to estrogen sulfates. Information regarding the expression of STS in human breast carcinoma tissues is still very limited compared to that of aromatase or 17beta-hydroxysteroid dehydrogenases (17beta-HSDs… (More)
DOI: 10.1111/j.1749-6632.2008.03683.x

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