New developments in biomarkers for melanoma.

  title={New developments in biomarkers for melanoma.},
  author={Klaus G Griewank and Selma Ugurel and Dirk Schadendorf and Annette Paschen},
  journal={Current opinion in oncology},
  volume={25 2},
PURPOSE OF REVIEW Therapy of malignant melanoma recently experienced remarkable advances with the introduction of two treatment regimens, gene mutation-based therapies with signaling pathway inhibitors (kinase inhibitors) and treatments with immune modulators. Both strategies prolong patients' survival but still have specific limitations, demanding the identification of additional genetic and immunological biomarkers as predictors of treatment response and prognosis. New developments in that… CONTINUE READING
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