New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells.

@article{PrezPersona2007NewCT,
  title={New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells.},
  author={Ernesto P{\'e}rez-Persona and Mar{\'i}a Bel{\'e}n Vidriales and Gema Mateo and Ram{\'o}n Garc{\'i}a-Sanz and Mar{\'i}a Victoria Mateos and Alfonso Garc{\'i}a de Coca and Josefina Galende and Guillermo Mart{\'i}n-N{\'u}{\~n}ez and Jos{\'e} Mar{\'i}a Alonso and Natalia de las Heras and Jos{\'e} Mariano Hern{\'a}ndez and Alejandro Mart{\'i}n and Consuelo L{\'o}pez-Berges and Alberto Orfao and Jes{\'u}s Fernando San Miguel},
  journal={Blood},
  year={2007},
  volume={110 7},
  pages={2586-92}
}
Monoclonal gammopathy of uncertain significance (MGUS) and smoldering multiple myeloma (SMM) are plasma cell disorders with a risk of progression of approximately 1% and 10% per year, respectively. We have previously shown that the proportion of bone marrow (BM) aberrant plasma cells (aPCs) within the BMPC compartment (aPC/BMPC) as assessed by flow cytometry (FC) contributes to differential diagnosis between MGUS and multiple myloma (MM). The goal of the present study was to investigate this… CONTINUE READING
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Differentiation of monoclonal gammopathy of undetermined significance and multiple myeloma using PROGRESSION CRITERIA IN MGUS AND SMM 2591 BLOOD

  • O Sezer, U Heider, I Zavrski, K. Possinger
  • VOLUME 110,
  • 2007
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