New concepts in HIV-1 vaccine development.

  title={New concepts in HIV-1 vaccine development.},
  author={Kathryn E. Stephenson and Helen T D'Couto and Dan H Barouch},
  journal={Current opinion in immunology},
With 2 million people newly infected with HIV-1 in 2014, an effective HIV-1 vaccine remains a major public health priority. HIV-1 vaccine efficacy trials in humans, complemented by active and passive immunization studies in non-human primates, have identified several key vaccine-induced immunological responses that may correlate with protection against HIV-1 infection. Potential correlates of protection in these studies include V2-specific, polyfunctional, and broadly neutralizing antibody… CONTINUE READING
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HVTN 097 evaluation of the RV144 vaccine regimen in HIV uninfected South African adults

  • GE Gray, E Andersen-Nissen, +7 authors S Phogat
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