New colorimetric method for the determination of nystatin.

@article{Amer1975NewCM,
  title={New colorimetric method for the determination of nystatin.},
  author={Mohamed Amer and A A Habeeb},
  journal={Talanta},
  year={1975},
  volume={22 7},
  pages={605-7}
}
A new colorimetric method for the determination of nystatin is reported, based on the reaction of the alkaline hydrolysis product of nystatin with p-aminoacetophenone in presence of concentrated hydrochloric acid. The proposed method determines 0.2-1.0mg of nystatin with recovery of 100.7 +/- 1.2%. The method is adopted to the determination of nystatin in pharmaceutical preparations, and interference due to the presence of sugar is eliminated.