New clues about vitamin D functions in the nervous system

@article{Garcion2002NewCA,
  title={New clues about vitamin D functions in the nervous system},
  author={Emmanuel Garcion and Nelly Wion-Barbot and Claudia N. Montero-Menei and François Berger and Didier Wion},
  journal={Trends in Endocrinology \& Metabolism},
  year={2002},
  volume={13},
  pages={100-105}
}
Accumulating data have provided evidence that 1 alpha,25 dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] is involved in brain function. Thus, the nuclear receptor for 1,25-(OH)(2)D(3) has been localized in neurons and glial cells. Genes encoding the enzymes involved in the metabolism of this hormone are also expressed in brain cells. The reported biological effects of 1,25-(OH)(2)D(3) in the nervous system include the biosynthesis of neurotrophic factors and at least one enzyme involved in… 
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Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System
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A greater role for calcitriol may be envisioned in the peripheral nervous system, as it is involved in myelination, axonal homogeneity of peripheral nerves, and neuronal-cell differentiation.
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