New clues about vitamin D functions in the nervous system

@article{Garcion2002NewCA,
  title={New clues about vitamin D functions in the nervous system},
  author={E. Garcion and N. Wion-Barbot and C. Montero-Menei and F. Berger and Didier Wion},
  journal={Trends in Endocrinology & Metabolism},
  year={2002},
  volume={13},
  pages={100-105}
}
  • E. Garcion, N. Wion-Barbot, +2 authors Didier Wion
  • Published 2002
  • Biology, Medicine
  • Trends in Endocrinology & Metabolism
  • Accumulating data have provided evidence that 1 alpha,25 dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] is involved in brain function. Thus, the nuclear receptor for 1,25-(OH)(2)D(3) has been localized in neurons and glial cells. Genes encoding the enzymes involved in the metabolism of this hormone are also expressed in brain cells. The reported biological effects of 1,25-(OH)(2)D(3) in the nervous system include the biosynthesis of neurotrophic factors and at least one enzyme involved in… CONTINUE READING
    736 Citations
    Vitamin D3—implications for brain development
    • 114
    Vitamin D and cancer
    • 260
    Distribution of the Vitamin D receptor and 1α-hydroxylase in human brain
    • 928
    Involvement of PI3-K in neuroprotective effects of the 1,25-dihydroxyvitamin D3 analogue - PRI-2191.
    • 10
    • PDF
    Vitamin D, nervous system and aging
    • 72
    • PDF
    Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain.
    • 580
    • PDF
    Vitamin D and the brain: Genomic and non-genomic actions
    • 73
    Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System
    • 3
    • PDF

    References

    SHOWING 1-10 OF 102 REFERENCES
    Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction
    • D. Panda, D. Miao, +4 authors D. Goltzman
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2001
    • 534
    • PDF
    1,25-dihydroxyvitamin D3 regulates the synthesis of nerve growth factor in primary cultures of glial cells.
    • 207
    1,25-Dihydroxyvitamin D3 regulates the expression of the low-affinity neurotrophin receptor.
    • 65