New cardiac expression of two adenosine-2A receptor isoforms in dysfunctioning minipigs.

PURPOSE Eight A2AR variants are reported in humans while no A2AR isoforms in pigs. The aim of this study was to evaluate potential isoforms presence in cardiac pig tissue to better define possible involvement of A2AR in the cardiovascular pathophysiology. MATERIALS AND METHODS In adult male minipigs (n = 4) left ventricular dysfunction (LVD) was induced… (More)