New cardenolides from the stem bark of Trewia nudiflora.

  title={New cardenolides from the stem bark of Trewia nudiflora.},
  author={Jamil A. Shilpi and Alexander Ian Gray and Veronique Seidel},
  volume={81 6},
Phneological Studies on Trewia Nudiflora
Trewia nudiflora Linn belongs to plant genus of the spurge family Euphorbiaceae, sub-family Acalyphoideae and is one of the important medicinal plants in Indian systems of medicine like Ayurveda,
Antibacterial, Antioxidant and Cytotoxic activities of Trewia nudiflora
The aim of the study is to verify the traditional uses of different parts of Trewia nudiflora. Leaves, fruits, twigs & seeds of T. nudiflora were extracted with ethanol to evaluate antibacterial,
Total Synthesis and Biological Evaluation of 19-Hydroxysarmentogenin-3 -O-α-l-rhamnoside, Trewianin, and Their Aglycons.
The significantly higher activities of 1a and 1b in comparison to 2a and 2b demonstrated the biological importance of the monosaccharide substructure.
Concise Enantioselective Total Synthesis of Cardiotonic Steroids 19-Hydroxysarmentogenin and Trewianin Aglycone.
The expedient and scalable approach to cardiotonic steroids carrying oxygenation at the C11- and C19-positions has been developed and applied to the total asymmetric synthesis of steroids
Toxicity of Trewia nudiflora-mediated silver nanoparticles on mosquito larvae and non-target aquatic fauna
Abstract In this study, we synthesized and characterized (UV–vis, XRD, FTIR, SEM, TEM, and AFM) Trewia nudiflora-assisted silver nanoparticles (Tn-AgNPs). The toxicity of T. nudiflora leaf aqueous
Antidiabetic, antihyperlipidemic and antioxidant activities of aqueous and ethanol extracts of leaves of Trewia nudiflora Linn in alloxan induced diabetic rats
It is concluded that aqueous and ethanol extracts of leaves of Trewia nudiflora possess antidiabetic, antihyperlipidemic and antioxidant activities.
Chemical synthesis of saponins: An update
  • Peng Xu, Biao Yu
  • Chemistry
    Advances in Carbohydrate Chemistry and Biochemistry
  • 2021


Chemical constituents from the stem bark of Trewia nudiflora
Trewia nudiflora L. is the only member of the genus Trewia (Euphorbiaceae), which is mainly distributed in India, Malaysia, and southwest of China. Previous studies have shown that the seed of T.
Terpenoids and Aromatic Compounds from Euphorbia heteradena
Euphorbia heteradena Jaub. & Spach (Euphorbiaceae), a plant endemic to Turkey, has not been investigated previously. The CH2Cl2 extract of the aerial parts of Euphorbia heteradena yielded
Chemical constituents from the stem bark of Trewia nudiflora L. and their antioxidant activities.
Three new compounds, namely, (+)-dihydrodehydrodiconiferyl alcohol 4- O- beta-(6' O-galloyl)-glucopyranoside, together with eleven known ones, were isolated from the stem bark of Trewia nudiflora and elucidated by means of 1D, 2 D NMR and HR-MS analyses.
Chemical constituents from the pericarp of Trewia nudiflora
Three new ent-atisane diterpenes, i.e., 17-hydroxy-ent-atisan-19-oic acid (1), 17-hydroxy-ent-atisan-19-oic acid methyl ester (2), and 16alpha,17-dihydroxy-ent-atisan-19-al (3), together with five
A rare new cleistanthane diterpene from the pericarp of Trewia nudiflora
A minor, unprecedented diterpene, 3 beta,17-dihydroxycleistantha-12,15-dien-2-one (1), was isolated from the CHCl3-soluble part of the EtOH extract of the pericarp of Trewia nudiflora. The structure
3'-epi-19-Norafraside and 12β-Hydroxycoroglaucigenin from Asclepias curassavica
3'-epi-19-Norafraside, a 19-norcardenolide glycoside with dual linkages between a cardenolide and 4, 6-dideoxy-galactos-2-ulose, and 12β-hydroxycoroglausigenin were newly isolated from the stems of
Complete 1H and 13C signal assignments of 5β‐cardenolides isolated from Acokanthera spectabilis Hook F.
Four cardiotonic glycosides were isolated from Acokanthera spectabilis. Their structures and conformational behaviour were investigated by extensive application of one‐ and two‐dimensional 1H and
Cardenolides and cardiac aglycone from the stem bark of Trewia nudiflora
Five new cardenolides and one new cardiac aglycone, i.e., (5 alpha)-sarmentogenin 3-(alpha-L-rhamnopyranoside) (1), (5 alpha)-sarmentogenin (2), 11-oxouzarigenin 3-(alpha-L-rhamnopyranoside) (3), (5