New assays for parathyroid hormone (PTH) and the relevance of PTH fragments in renal failure.

@article{Goodman2003NewAF,
  title={New assays for parathyroid hormone (PTH) and the relevance of PTH fragments in renal failure.},
  author={William G. Goodman},
  journal={Kidney international. Supplement},
  year={2003},
  volume={87},
  pages={S120-4}
}
BACKGROUND Immunometric assays for parathyroid hormone (PTH) are used extensively to assess bone and mineral metabolism in patients with end-stage renal disease (ESRD) who are treated with dialysis. Results generally correspond to bone histology as documented by bone biopsy, and they are useful in monitoring disease progression. Recent work has shown, however, that older, first-generation immunometric PTH assays detect not only full-length PTH(1-84), but also other amino-terminally-truncated… CONTINUE READING