New aspects on angiotensin-converting enzyme: from gene to disease.

  • Bruno Baudin
  • Published 2002 in Clinical chemistry and laboratory medicine

Abstract

Angiotensin-converting enzyme (ACE) is a well known zinc-metallopeptidase that converts angiotensin I to the potent vasoconstrictor angiotensin II and that degrades bradykinin, a powerful vasodilator, both for regulation of vascular tone and cardiac functions. Other natural substrates of ACE were identified broadening the functions of this enzyme within… (More)

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