New aspects of natural-killer-cell surveillance and therapy of cancer

  title={New aspects of natural-killer-cell surveillance and therapy of cancer},
  author={M. Smyth and Y. Hayakawa and K. Takeda and H. Yagita},
  journal={Nature Reviews Cancer},
  • M. Smyth, Y. Hayakawa, +1 author H. Yagita
  • Published 2002
  • Biology, Medicine
  • Nature Reviews Cancer
  • Natural-killer (NK) cells form a first line of defence against pathogens or host cells that are stressed and/or cancerous. NK cells express surface receptors that receive signals from the environment and determine their response to foreign or malignant cells. NK cells respond to these signals by producing effector molecules that can both directly suppress tumour growth and convey important information to the rest of the immune system. We have only recently begun to appreciate the potential for… CONTINUE READING
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